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tecovirimat will boost the degree or influence of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor. Tecovirimat is often a weak inhibitor of CYP2C8 and CYP2C19. Watch for adverse consequences if coadministered with sensitive substrates of those enzymes.fluvoxamine will improve the degree or effect of diazepam by influe